Selected Publications:

Simsek, D, Tiu GC, Flynn RA, Byeon, GW, Leppek K, Xu AF, Chang, HY, Barna M. The Mammalian Ribo-interactome Reveals Ribosome Functional Diversity and Heterogeneity. Cell 169 (6): 1051–65.e18, 2017.

Shi Z,Fujii K,Kovary KM,Genuth NR,Rost HL,
Teruel MN, Barna,M. Heterogenous Ribosomes Preferentially Translate Distinct Subpools of mRNAs Genome-wide. Molecular Cell 67:71-83, 2017.

Simsek D, Barna M. An emerging role for the ribosome as a nexus for post-translational modifications. Current Opinion in Cell Biology 45: 92–101, 2017.

Fujii K, Shi Z, Zhulyn O, Denans N, Barna M. Pervasive translational regulation of the cell signalling circuitry underlies mammalian development. Nature Communications 8:1443, 2017.

Xue S, Tian S, Fujii K, Kladwang W, Das R, & Barna M. RNA regulons in Hox 5'UTRs confer ribosome specificity to gene regulation. Nature (Article), 517(7532):33-8 2015.
Preview Article: Molecular Biology: Entry Signals Control Development. Nature 2014 Nov 19 doi: 10.1038/nature14069
Feature: Faculty of 1000
Additional supplemental information related to results presented in the manuscript.

Truitt M, Conn CS, Shi Z, Pang X, Tokuyasu T, Coady A, Seo Y, Barna M*†, Ruggero D*†. Differential requirements for eIF4E dose in normal development and cancer. Cell,162(1):59-71 2015.
*Co-Corresponding Author; † These authors contributed equally to this work.

Shi Z, Barna M. Translating the Genome in Time and Space: Specialized Ribosomes, RNA Regulons, and RNA-Binding Proteins. Annu Rev Cell Dev Biol. 31:31-54, 2015.

Xue S, Barna M. Cis-regulatory RNA elements that regulate specialized ribosome activity. RNA Biol. 2015 Sep 1:1-5

Barna M. The ribosome prophesy. Nature Reviews Molecular Cell Biology 16, 268, 2015.

Fairchild, CL & Barna,M. Specialized filopodia: At the tip of morphogen transport and vertebrate tissue patterning. Current Opinion in Genetics & Development 4; 27C:67-73, 2014.

Barna M, Ruggero D. Tailor Made Protein Synthesis for HSCs. Cell Stem Cell 14 (4): 423-4, 2014.

Sanders TA., Llagostera E, & Barna M. Specialized filopodia direct long-range transport of Shh during vertebrate tissue patterning. Nature, 497:628-32, 2013.
Preview Article: Filopodia: The Cellular Quills of Hedgehog Signaling? Developmental Cell 25:328-330, 2013.
Preview Article: Cytonemes extend their reach. EMBO 2013 May 14. doi: 10.1038/emboj.2013.115.
Feature: Faculty of 1000; received a 11.0 (“Exceptional”)

Barna M. Ribosomes take control. PNAS, 110: 9-10, 2013.

Xue S & Barna M. Specialized ribosomes: a new frontier in gene regulation and organismal biology.
Nature Reviews Molecular and Cellular Biology, 13: 355-69, 2012.

Kondrashov N, Pusic A, Stumpf CR, Shimizu K, Hsieh AC, Xue S, Ishijima J, Shiroishi T & Barna M. Ribosome mediated specificity in Hox mRNA translation and vertebrate tissue patterning. Cell 145: 383-397, 2011.
Preview Article: Topisirovic T & Sonenberg N. Translational Control by the Eukaryotic Ribosome. Cell 145: 333-334, 2011.
Research Highlight: Protein maker and gene regulator. Nature 473: 127, 2011.
Research Highlight: Gene Expression: Personalized Ribosomes. Nature Reviews Molecular Cell Biology 12:344-345, 2011.
Research Highlight: Nature Reviews Genetics 12:382, 2011.
Feature: Editors Choice in Cell Biology: Ribosomes in Control. The Scientist September 2011.
Feature: Faculty of 1000: received a 20.0 (top 2% of all evaluated articles).
Cell biology 2011: Signaling breakthroughs of the year. Science Signaling 5: p. eg 1, 2012.

Barna M*†, Pusic A, Zollo O, Costa M, Kondrashov N, Rego E, Rao PH, Ruggero D†. Suppression of Myc oncogenic activity by ribosomal protein haploinsufficiency. Nature 456: 971-975, 2008. *Co-Corresponding Author;
† These authors contributed equally to this work.
Research Highlight: Nature Reviews Cancer 9:4-5, 2009.
Feature: Faculty of 1000; received a 10.0 (“Exceptional”)

Barna M*, Niswander L. Visualization of cartilage formation: insight into cellular properties of skeletal progenitors and chondrodysplasia syndromes. Developmental Cell 12: 931-41, 2007.
*Co-Corresponding Author
Feature: Faculty of 1000; received a 10.0 (“Must Read”)

Barna M, Pandolfi PP, Niswander L. Gli3 and Plzf cooperate in proximal limb patterning at early stages of limb development. Nature 436: 277-81, 2005.

Costoya JA, Hobbs RM, Barna M, Cattoretti G, Manova K, Sukhwani M, Orwig KE, Wolgemuth DJ, Pandolfi PP. Essential role of Plzf in maintenance of spermatogonial stem cells. Nature Genetics 36:653-9 (2004). (Second Author)
Preview Article: Kotaja N & Sassone-Corsi P. Plzf pushes stem cells. Nature Genetics 36: 551-553, 2004.
Research Highlight: Developmental Biology: Talking about regeneration. Nature Reviews Genetics 5, 486- 487, 2004.

Barna M, Merghoub T, Costoya JA, Ruggero D, Branford M, Bergia A, Samori B, Pandolfi PP. Plzf mediates transcriptional repression of HoxD gene expression through chromatin remodeling. Developmental Cell 3: 499-510, 2002.

Barna M, Hawe N, Niswander L, Pandolfi PP. Plzf regulates limb and axial skeletal patterning. Nature Genetics (Article) 2000, 25:166-72.

Complete List of Published Work:

© 2014 Barna Lab, Stanford University